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The focus of our research was to use Myxococcus xanthusas a model system for the study of signal transduction, motility, and development in a complex bacterial system.
We identified two chemicals within the compound classes biphenyl amides and pyrazolo[1,5-α]pyridines, which reproducibly inhibit both xL3 and L4 motility and development, with IC50s of 14 47 μM.
In agreement with this notion, SDF-1 has been shown to play an important role in hematopoietic and progenitor stem cell motility and development in both human and murine (Koster, 2009; Wright et al., 2002).
Polarity plays a key role in cell differentiation, cell fate determination, cell motility, and development.
ExC7 (Figure 2, Table S1), which showed a steep and continued decline in abundance from an initial high, was enriched for genes involved in cell motility and development (P = 0.00002), cell adhesion (P = 0.0001) and blood coagulation (P = 0.003).
While to our knowledge no WD-repeat proteins have been characterized in Archaea, a small number have been characterized in bacteria, including AglU, which is required for gliding motility and development of spores in Myxococcus xanthus [79], and the Hat protein from Synechocystis sp. PCC6803, required for control of high affinity transport of inorganic carbon [80].
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Cyclic AMP signaling is essential for sperm development, motility, and maturation in the female genital tract (Visconti et al., 1995b; Wennemuth et al., 2003; Krähling et al., 2013).
Reported complications of pneumonectomy include mediastinal shift with herniation of the remaining lung, cardiac herniation, cardiac arrhythmias, bronchopleural fistula, esophageal motility disorders, and development of scoliosis [ 9- 11].
Mitogen-activated protein kinases (MAPKs) are critical signaling molecules to transmit extrinsic stimuli into diverse cellular processes including apoptosis, mitosis, cell motility, differentiation and development (Cuevas et al., 2007; Gallo and Johnson, 2002; Wagner and Nebreda, 2009).
All considered, observed up-regulations could reinforce cell adhesion and consequently exert a preventive effect on cell motility and metastasis development.
A complex relationship exists between swarming motility and biofilm development [ 12- 15].
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motility and density
motility and alignment
motility and pupillary
motility and viability
motility and morphology
motility and apoptosis
motility and mortality
motility and prostate
motility and percentage
motility and metastasis
motility and plasma
motility and ciliogenesis
motility and biocompatibility
motility and soma
motility and excretion
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