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The exclusive motifs in positive or negative dataset may be a major driver for this differential behavior; these motifs were explored using MERCI software.
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Biological significance of motifs is explored by analyzing the set of proteins containing the motif and the positions of predicted motif instances to determine GO enrichment, overlap with protein domains, and possible motif-motif interactions.
The presence of sequence motifs was explored using MEME suite software, section MEME (http://meme.nbcr.net) and confirmed by RSAtools software (http://rsat.ulb.ac.be/rsat/), section oligoanalysis with a default parameter selection for 5, 6 or 8 nucleotide lengths.
The occurrence and frequency of different SSR motif repeats in EST sequences of the two subspecies were explored (Table 3).
Plausible interactions were explored.
were explored.
Once a compelling motif has been identified from a set of ChIP data, the motif can be explored using the MochiView motif scoring utilities and the plot browser to identify instances of a motif that occur in intergenic regions but not within the binding regions called by the ChIP-analysis algorithm.
As with T. brucei, the dichlorobenzyl motif in 25 was explored, and this SAR study confirmed the importance of the 3,4-dihalophenyl substitution.
The function of the deca-GX3 motif has not been explored until now, but we speculate that it serves a role in Yae1-Lto1 heterodimer formation as in membrane proteins.
DNA containing unmethylated CpG dinucleotides, or CpG motifs, (CpG DNA) has been explored as a therapeutic agent, owing to its potent immunostimulatory activity.
Other motifs that were to be explored in depth in Kim's later work can also be found in Yangsan Province, such as animal imagery, particularly the use of hens as a representation of fertility and sexuality.
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