Your English writing platform
Free sign upSuggestions(5)
Exact(23)
While the morphology of poorly invasive MCF-7 and LNCaP cells was not modulated by any of the peptide motifs, the aggressive PC-3 cells exhibited an invasive morphology when cultured in hydrogels comprising IKVAV and GFOGER motifs compared to RGD motifs or nonfunctionalised controls.
Larger peaks, as defined by the number of reads in the peak, more often have TCF4 binding motifs compared to weaker ones (Fig. 3A).
To identify further distinguishing features of demethylation-sensitive and -resistant CGs, we also analyzed if genes harbouring demethylation-resistant CGs are characterized by different sets of transcription factor binding motifs compared to genes that become demethylated.
As in the size-3 motifs, interneurons are significantly enriched within the computational motifs (68% of neurons in size-4 significant motifs, compared to the baseline abundance of 29% in the network as a whole).
However, M. smegmatis, R. africae, C. glutamicum, T. denticola and S. suis possessed more eukaryotic-like motifs compared to their "bad bug" relatives, but this difference was not statistically significant (p>0.05) (Supporting Information S1; Supporting Information S2).
In fact, the list of motifs in Fig. 4 is clearly dominated by interneurons, (69% of the neurons in the list of 40 motifs, compared to only about 29% of all neurons in the full network of 279).
Similar(37)
To confirm GADD45G as a bona fide direct target of OCT4, we performed a ChIP-real-time-PCR reaction, and confirmed the fold enrichment immediately flanking the OCT4 motif compared to neighbouring sites.
(B ) Agadir prediction for helical stability of the 7-turn helix motif compared to wild-type AH.
These small peptides were defined as 'simple Kunitz' (SK) due their atypical Cys motif compared to archetypal Kunitz-domain peptides.
Normalizing to the INPUT performed best, which yielded the highest percentage of exonic peaks and the GGAG motif compared to the other three methods.
However, it should be considered that this depletion was calculated on the basis of parameter I ("number of promoters with a motif") compared to a randomized background dataset.
Write better and faster with AI suggestions while staying true to your unique style.
Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.
Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com