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Exact(5)
The monomeric form of PrgI is a helix-turn-helix motif with two symmetrically charged surfaces and a conserved loop region, PxxP domain, which are important for needle assembly [15] [17].
The third motif with two conserved histidines (HxxxH) resides at the beginning of the seventh predicted core transmembrane segment.
Furthermore, these do-not-care positions are often consecutive, forming a motif with two short conserved regions with some fixed distance in between.
However, introduction of the G4 motif with two point mutations that render it incapable of forming an intramolecular G4 structure in vitro (Fig 3B) did not induce instability of Bu-1a expression (Fig 3A).
The DNA-binding domain of TAL effectors (TALEs) consists of up to 30 tandem repeats of a 33-amino acid to 35-amino acid motif with two variable residues [termed the repeat variable di-residues (RVDs)] that confer single nucleotide specificity to each repeat so that the repeats linearly define the nucleotide sequence of the binding site (Boch et al. 2009; Moscou and Bogdanove 2009).
Similar(55)
We then considered the entire metal-binding motif with four residues and calculated the interaction energies with the copper ion.
β-propeller proteins are highly symmetrical, being composed of a repeated motif with four anti-parallel β-sheets arranged around a central axis.
The crystal structure of complex 1 was determined by single crystal X-ray diffraction, which adopts the paddlewheel motif with four bidentate carboxylate ligands joining two Cu II) ions.
Recent work in designing and synthesising molecules displaying the phenomenon of "single molecule magnet" (SMM) behaviour has shown how a propeller motif with four paramagnetic metal centres can both stabilise non-zero ground spin states and display slow relaxation of the hysteresis: the signature of an SMM.
Meyer Schapiro compares the motif with one in an initial in the later Book of Kells.
Note that we extended the original motif with one extra position (position -5) at the N-terminus.
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