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There is the quest motif, which is as old as Arthurian legend.
We designed decoy oligonucleotides, composed of several repeats of a RNA motif, which is recognized by a single SF.
They lack the (N/D DxxD motif which is characteristic for many other prenyltransferases.
We also focused on the flexible DFG motif, which is closely connected to kinase activation and inhibitor binding.
The tetrapeptide does not include an ETGE motif, which is a commonly found consensus sequence in known peptidic inhibitors.
This was a slightly changed version of the Polynesian motif, which is found in parts of Indonesia.
Complex 2 shows a 1D structural motif, which is further assembled into a 3D supramolecular architecture by hydrogen bonds and packing interactions.
Its carbohydrate-binding site contains a QPD (Gln-Pro-Asp) motif, which is generally recognized as the galactose specificity-determining motif in the C-type lectins.
Compound 1 features a 42-membered bimetallic macrocyclic structural motif which is extended by mal groups to form a 2D network.
An azepinone motif, which is inherent in the structures of many well studied protein kinase inhibitors, serves as prominent structural feature of the new compounds.
Furthermore, the two-dimensional arrangement adopts double-edged axe-shaped motif, which is different from the common herringbone or brick-wall pattern in coordination polymers.
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CEO of Professional Science Editing for Scientists @ prosciediting.com