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The ligand binding cavity extends from the helix-turn-helix motif, which functions as a portal region for fatty acids.
Both MLPK forms have an N-myristoylation motif, which functions as a plasma membrane targeting motif.
HD1 houses the GxP motif which functions to hold the nucleotide in position and HD2 in NLRC4 contacts the LRR in the inhibited conformation [21,19].
The predicted amino acid sequence of atf-6α from yellow catfish and other species are characterized by a cytoplasmic N-terminus that contains a bZIP motif, which functions as a transcription factor following regulated intramembrane proteolysis in ER-stressed cells (Ishikawa et al. 2011).
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The N-terminal domain includes a catalytic region with a helix hairpin helix (HhH) motif, as well as a pseudo-HhH region and iron sulfur cluster loop (FCL) motif, which function in the recognition and excision of adenine moieties opposite 8-oxoG [Guan et al., 1998; Lukianova and David, 2005].
Potentially, KTF1 is also missing since the OrthoMCL group protein isolated lacks GW/WG motifs, which function to interact with AGO4 and siRNAs (He, Hsu, Zhu, et al. 2009).
Thus, RFHVMn LANA contains a distinct monopartite Lys/Arg-rich motif, 40ARKRRKG46, which functions similarly to the KSHV 24RKRNRSP30 motif.
The AMY motif (TATCCA) appears to be more frequent in IR64-Sub1 downregenesed genes, whereas the AMY3 motifs (CGACG), which functions as a G-box coupling element, is more prevalent in upregulated genes.
S100 proteins are small calcium-binding proteins of the EF hand motif which can function as both intra- and extracellular signaling molecules.
The focus here is on two protein interaction domains, the RING finger and WD40-associated ubiquitin-like (RAWUL) and Sterile Alpha Motif (SAM), which function within the multiprotein assembly called Polycomb repression complex 1 (PRC1) and are instrumental in creating the precise three-dimensional state of chromatin.
scaRNAs are larger than the predominant classes of snoRNAs and display characteristic boxes of both C/D and H/ACA snoRNAs as well as CAB boxes (motif UGAG) which function as a Cajal body localization signal [9].
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