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A genetically engineered Escherichia coli (E. coli) strain displaying glucose dehydrogenase (GDH) with ice-nucleation protein (INP) as the anchoring motif was first constructed.
Because the motif was first described in the work L'architettura (1537), by the Italian architect Sebastiano Serlio, it is also known as the Serlian motif, or Serliana, and the window derived from it may be called a Serlian window.
The GntR family of bacterial regulators that possess the helix-turn-helix motif was first described by Haydon and Guest (1991), and comprises approximately 270 members.
This motif was first seen in the bovine pancreatic trypsin inhibitor (BPTI -like proteinase inhiBPTI -likeich are exceproteinasestrong inhibitors of serine proteinases (also knowhich S1arerotexceptionallystrongsinhibitorsmofrypserine
The [YFW]XC motif was first reported in the powdery mildew fungus Blumeria graminis [ 51].
The EF-hand motif was first described in the crystal structure of parvalbumin [ 62].
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In terms of effect size (reduction in deviance), the CGCGC motif was second after H3K4me3, and R-loop formation potential was a distant last [see Additional file 1: Table S4].
The length of the motif is first sampled from a user-specified range and then nucleotide probabilities at each position are filled randomly.
The occurrence of α-glucan oligosaccharide structural motifs was first corroborated through the resolution of the crystal structures of several oligoosaccharides including maltotriose, panose, and isopanose, allowing predictions to be made about some of the structural features of the amylopectin branch point, as first described by Imberty and Pérez.
Interactions between these structural motifs were first proposed upon the double substitution M204V+L180M encoding LVDr [18].
These motifs were first described in Drosophila, where they exist as repeat motifs, in association or not, with other conserved motifs (such as a Ring motif).
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