Sentence examples for motif to guide from inspiring English sources

Transcription factors vary in their requirement for a consensus motif to guide their selection of genomic binding sites [5].

C′/D′ motifs were also highly conserved in snoRNAs that do not appear to use this motif to direct methylation; the 'guide' region adjacent to the D′ motif in each of these RNAs was not conserved and no target has been identified (Supplementary Figure S1).

71 The second strategy consists in using motif recognition algorithms that integrate additional information to guide the motif search.

Expression, binding, and cross-species conservation data have all been used to guide motif discovery methods.

MEMERIS is an extension of the popular MEME algorithm that uses RNA accessibility as a prior probability to guide motif finding to single-stranded regions [ 122].

Hiller et al. extended MEME by adding a pre-computing procedure to measure single-strandedness of RNA sequence as a prior knowledge to guide the motif search.

In fact, MEMEris 72 uses RNA secondary structure to guide the motif search toward single-stranded regions, and PhyloGibbs 74 integrates conservation information.

We have performed a rigorous and systematic analysis of the available experimental GPCR structures, identifying common, different and unique sequence and structural motifs that can be used to guide template selection for homology modelling.

A few examples, including known eukaryotic linear motifs are given in the help to guide the user with the format.

Functional characterization of these ADAMs (and specific motifs) in X. tropicalis may provide useful information to guide future research on human development and diseases.

Accurate motif discovery is difficult in general, but incorporating additional information to guide the search for novel sequence signals can improve performance.