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Interaction with PCNA is mediated by a PIP-like motif that differs somewhat from the canonical version in terms of sequence and conformation, whereas the SIM SUMO interaction closely resembles that of other known examples.
In D. melanogaster, phosphorylation sites (including one Polo-box domain binding motif and one Plk-phosphorylation motif, that differs at one amino acid site from the canonical sequence D/E-X-S/T-Ø-X-D/E where Ø is an hydrophobic amino acid), have been reported [28].
GLTP also forms a membrane targeting motif that differs from those used by other important peripheral proteins, i.e., C1, C2, PH, FYVE, and PX domains.
Rab proteins exhibit also a characteristic C-terminal prenylation motif that differs from the motifs found in Ras and Rho families, i.e. CAAX, where C denote cysteine, A – aliphatic residue and X – any residue [ 14].
In this study, nominal variant sequences were classified as SNP variants if they displayed a repeat motif that differs from the commonly-described motif, an occurrence indicative of point substitution.
Similar(55)
The only exception was tetraodon, which had a preferred SP1 motif that differed from the GC box at two nucleotide sites, most commonly appearing as a variant similar to the GA box (AGG AG G.
To find motifs that differ in frequency between different regulatory modes, the redundancy ratios of genes with and without each motif were compared using Wilcoxon's rank-sum test.
The diploid genome allows us to identify binding motifs that differ between alleles and that correspond to differences in chromatin accessibility.
Each σ factor recognizes promoter motifs that differ in their consensus DNA sequence.
In fact, motifs that differ in one, two and three base pairs from the four never-found human nullomers occur with increasing frequencies consistent with the effects of CpG hypermutability.
All target genes had this core binding motif present in their upstream sequences except for two of the ten target genes, which had binding motifs that differed from the consensus binding motif in two nucleotides, namely, TTTTAAC and AGTTTCC.
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