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Both peptides were shown to be highly toxic in mice and displayed the cysteine-stabilized α-helical motif that characterizes endothelins and short-SRTXs, to which a longer C-terminus with variable flexibility is added.
The AVR proteins of oomycete plant pathogens carry a N-terminal type II secretion signal peptide, followed by a conserved RXLR motif that characterizes a domain known to function in translocating the effectors into host cells [10] [12].
This analysis was difficult since i) the similarity between known AHLases is low (ca. 25% identity); ii) a part of the motif that characterizes AHLase (HXHXDH) is shared by several unrelated families of proteins (metallo-b-lactamase, glyoxalase II and arylsulfatase).
2. Construct a motif that characterizes the set of words found in step 1.
More surprising was the finding that no OdH2As contained the PIKK substrate SQE/DΦ phosphorylation motif that characterizes all H2AXs.
First, they completely lacked the repetitive asparagine-rich C-terminus motif that characterizes their H. melpomene counterparts (Fig 5).
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While it appears that even in this case we could identify the basic structural motifs that characterize the conformational landscape of this system, the correlation with energy is very poor.
In a naïve Bayes classifier, we thus integrated previously-defined PSSMs characterizing the phosphorylation sites of human Ste20p-related kinases [13] with motifs that characterize the substrates of Ste20p identified in our biochemical screen.
Three distinct domains were identified in the S. pyrenaicus Wt1 isolate (Figure S2): a Wilm's tumour specific domain, and two (of the four) zinc finger DNA-binding motifs that characterize the C terminus of this transcription factor.
We identify motifs that characterize tissue specificity of lncRNA in thyroid and in prostate.
Bracovirus PTP sequences carry the 10 conserved motifs that characterize the protein tyrosine phosphatase domain defined in vertebrate PTPs [ 29].
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