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Motif sequence is highlighted in red and CpG in blue.
In mammals, the consensus Kozak motif sequence is reported as CACCATGG, with the start codon underlined [8].
The M3 motif sequence is conserved among all long PINs.
Some studies have indicated that motif sequence is associated with TF function.
We also observed that in paralogous genes containing DUAYAWUW, the motif sequence is highly conserved (i.e., the motif sequence is typically identical between paralogs) and that no correlation exists between motif diversity and K s (data not shown).
In Nipponbare, most of the motif sequence is CACACACGCA and in Pokkali, the motif is CACACACACA (fig. 8 B).
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SOX3 motif sequence was enriched in its target genes with the median relative enrichment score of 0.95.
Two decoy oligonucleotides, differing by a single nucleotide in the motif sequence, were designed against SRSF1; SF2i1 (5′ (CACAGGA n, n = 3 repeats) and SF2i2 (5′ (CGCAGGA n, n = 3 repeats) (Fig. 1a, Supplementary Table 1).
This number becomes substantially smaller when also the sites that still contain the CTCF motif sequence are considered in this analysis.
The 100 nt flanking sequence upstream and downstream around candidate poly(A) motif sequence were utilized.
Each PabHLH motif sequence was then used to conduct in-group phylogenetic analysis with DmbHLH motif sequences.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com