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This paper describes two- and three-dimensional coupled HM finite-element simulations with the MOTIF (Model Of Transport In Fractured/porous media) code.

Using a curated training set, a motif model of the leader peptide was built and used to screen over 120 fully sequenced bacterial genomes.

The 'performance measures' describe whether the motif detection tool is able to retrieve the motif model of the embedded motif in a particular test.

Plant cis-regulatory motifs are often reported as consensus sequences, a motif model of limited predictive power [ 4].

For the comparison of non-prevalent with prevalent splice forms, the scores are computed with respect to a motif model of prevalent instances; for the comparison of prevalent and constitutive splicing the scores are computed with respect to a model of the constitutive splice sites.

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The resulting motif models, of lengths 17 and 13, were searched against the individual families TIGR01323, TIGR03793, TIGR03795, TIGR03798 and the set of 20 proteins that resulted from PSI-BLAST [ 62].

The sequence motif models of each group of CRPs constructed by Silverstein et al.[ 63] were used as queries to blast against the AGPv2 5b filtered gene set peptide database [ 16].

Four such composite models were made by adding the conserved C-terminal motif model to each of the four CTDUF models.

As defined above, the most commonly used motif models for predicting the location of TFBSs are termed PSSMs.

We first used the motif models to identify all single occurrences of ABRE and CE3 in Arabidopsis and rice promoters.

The reason that we choose 7 as the main length of motif model is because 7 is one of the most common lengths of a motif core.

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