Sentence examples for motif makes it from inspiring English sources

[30] The broad motif makes it unlikely that different CAPN3 mutations cause an LGMD phenotype due to the deregulation of only one or two substrates.

The unusual spacing between C and H residues in the zinc-binding motif makes it difficult to search for homologies.

The repeat nature of the coiled-coil motif makes it difficult to clearly determine sequence homology relationships between long coiled-coil proteins.

Such a higher complexity of the signature for the dinucleotide-binding motif makes it possible to discriminate more precisely between the three isoforms: (i) the hexapeptide GAGNVA is found for GDH4 from Viridiplantae; (ii) the hexapeptide GSGNVA is the signature for GDH4 from not Viridiplantae (subset G).

The short size of the motif makes it tempting to speculate that the motif itself may have arisen independently (i.e. in repeated cases it may have evolved within sequence that was already part of the gene, rather than via a recombination event).

Of these, only RBM22 has an RNA-binding motif, making it a potential candidate for directly binding to the lariat-intron intermediate.

This is partly because the sequence data used in generating regular expression patterns may contain overrepresented residues that may have no functional role in the motif, making it difficult to differentiate association from functional necessity.

These data, combined with the fact that sialidase is a surface protein carrying a cell wall-anchoring LPXTG motif, make it a potentially valuable target for creating vaccines against P. acnes-associated diseases, such as acne vulgaris.

More importantly, however, the GAA_AAA_A sequence is in a different frame from the −1 PRF X_XXY_YYZ shift site motif, making it inconsistent with the tandem −1 slippage model.

Inspection of the EamA alignment (additional file 4: dmt.aln.tgz) reveals that the conservation of these glycines are 81%and68%8%, respectively, in the glycine-6-glycine motif, making it the most conserved intra-helical motif in the EamA alignment.

The definition of the structure of human progranulin as a glycoprotein bearing multiple copies of the granulin motif made it apparent that granulin peptides are generated through proteolytic cleavage of this precursor within the phagolysosomal compartment of the neutrophil.