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A third conserved short stretch (PAL motif) is typically present in the C-terminal regiof of presenilin genes and is also considered to have a functional role [12].
The Sensor 1 motif is typically found adjacent to the Walker A and B motifs and interacts with or "senses" the γ-phosphate of ATP (Figure 3) [24].
For these basal pilin subunits, the sortase recognition motif is typically located at the end of a long (35 Å), proline-rich, extended peptide that is well separated from the body of the protein [47].
This motif is typically described by [LIVMA]-X3- [ASCVTN]-X.
Similarily to class 2, GxxxG motif is typically present on one of the two helices.
Repeating of the motif is typically associated with a cooperative factor binding.
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The genes annotated directly 5' to the motif are typically syntenous with those in ' Cand.
Binding sites conforming tightly to the LexA-binding motif are typically located near or overlapping the RNA-polymerase binding-site on the promoter region of SOS genes [ 5].
For instance, the maximum fraction of the changes in TF binding between C57BL/6J and Caroli/EiJ that might be assigned purely to genetic changes in the bound motif was typically near a quarter of the total (31.2% [CEBPA], 29.6% [HNF4A], and 27.5% [FOXA1]).
For 2-MIB synthases from other microorganisms within this alignment, motifs are typically aspartate-rich: DDxxxE and NDxxSxxxE.
The TF binding motifs are typically short sequences with a narrow length distribution [3], [9], since a TF selectively binds 5 10 bases and not much more.
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