(c) Predicted secondary structures of the two families of Y RNA identified in H. polygyrus secretion products based on RNAfold, the conserved UUAUC motif is noted in blue.
The function of this novel putative domain is unknown, but the motif is noted to be valine rich, and in at least four cases, the DART motif is a site of regulated intramembrane proteolysis (RIP).
Similar to phylogenetic analyses, differences between YcdY ycdX and YcdY hflC-mdaB motifs were noted and may identify key residues/regions that can guide further subfamily member structure-function analyses.
Of these, 87 sequences that contained at least two TIR/CC-specific motifs, or three NB-ARC specific motifs, were noted as potential errors in automated gene calling or annotation and carried forward into the candidate set pending a manual check, to give a total of 564 putative NB-LRR DMP sequences.
G-quadruplex or G4 DNA is a unique form of four-stranded non-B DNA structure that engages certain G-rich sequences, presence of such motifs has been noted within telomeres.
First, GXXXG and related AXXXA motifs have also been noted to stabilize helix helix interactions and the folded states outside the lipid bilayer and in soluble proteins.
Conserved amino acid motifs have previously been noted in alignments of human, mouse and zebrafish OR sequences [ 13, 27, 30, 31] and these motifs include some of the amino acid residues highlighted above.
It might be noted that motifs from the first groups are the simplest, being homorepeats with an adjacent amino acid.
It should be noted that the motif of birth is one of Eckhart's favorites, for example, when he holds that the divine Father bears his Son in the soul, more precisely: in the ground of the soul, and in this way he bears me as himself and himself as me.
However, it should be noted that SSR motif frequencies are not necessarily indicative of phylogenetic relationships [ 64].
Additionally, it has been noted that stable motifs are more common than unstable ones even in post-transcriptional signal transduction (Milo et al., 2002), suggesting again a role for Qualitative Stability in these networks.
