Sentence examples for motif forms a from inspiring English sources
Sequence alignments and 3D molecular modelling of human type II cystatins indicate that this motif forms a 'back-side loop' located opposite the papain-binding surface.
The Arg residue of this motif forms a salt bridge (ionic lock) with Glu6.30 of TM6 that stabilizes the GPCR inactive state [28].
Here we show that Hfq belongs to the large family of Sm and Sm-like proteins: it contains a conserved sequence motif, known as the Sm1 motif, forms a doughnut-shaped structure, and has RNA binding specificity very similar to the Sm proteins.
The independently expressed central TSR of murine ADAMTS-1 required 0.46 to 0.66 M NaCl for elution from a heparin affinity column, indicating that this motif forms a functional heparin-binding unit [ 16].
The cysteine residue of this motif forms a conserved intramolecular disulfide bridge with a second conserved cysteine residue located in sialylmotif L. This S-S bond is essential for correct folding and enzymatic activity of ST8Sia [ 28].
Analysis of the Cep3 structure shows that this motif forms a disordered loop between residues 570 and 587, the base of which is directly adjacent to the N-terminal of the protein, where the linker and zinc cluster emerge (Fig 5A).
Similar to observations in the crystal structure of opsin the arginine of the DRY motif in TMH3 (in the TSHR an ERW motif) forms an H-bond interaction with the Gαq backbone at Y350 in the α5 C-terminal tail.
The ACGT core motif forms an important class of cis-elements implicated in a variety of functions.
In addition, the conserved Trp117 residue of the hash motif forms an important π-stacking interaction with the hydantoin moiety.
Closer inspection of the TRPM7 dimeric kinase domain structure revealed that the dimerization motif forms an extended α-helix which undergoes extensive interactions with a region in the kinase domain of the other monomer termed the 'dimerization pocket' [ 22].
The YSNS motif formed a β turn crucial for biological activity.
