Your English writing platform
Free sign upExact(5)
A pyrimidin-4-yl-urea motif forming a pseudo ring by intramolecular hydrogen bonding has been designed to mimic the pyrido[2,3-d]pyrimidin-7-one core structure of a well-established class of protein kinase inhibitors.
The SC consists of a repeating double-molecule motif forming a 1D tape as shown below.
A brief sequence rich in glycine and serine residues follows the conserved motif, forming a region of high predicted flexibility (data not shown).
Finally we study the interlerlocked negative feedback loop, i.e. a 2-gene motif forming a loop where the nodes respectively activate and repress each other, and show situations where this system possesses a resonance under periodic stimulation.
Each protomer features a N-terminal zinc finger domain and an α-helical tetramerization motif forming a rigid unit, followed by a flexible linker and an α-helical core domain.
Similar(55)
The YSNS motif formed a β turn crucial for biological activity.
Sequence alignments and 3D molecular modelling of human type II cystatins indicate that this motif forms a 'back-side loop' located opposite the papain-binding surface.
The Arg residue of this motif forms a salt bridge (ionic lock) with Glu6.30 of TM6 that stabilizes the GPCR inactive state [28].
Here we show that Hfq belongs to the large family of Sm and Sm-like proteins: it contains a conserved sequence motif, known as the Sm1 motif, forms a doughnut-shaped structure, and has RNA binding specificity very similar to the Sm proteins.
In this study, the cysteine beside NGR motif formed a cyclic via a disulfide linkage and the direct labeling method resulted in a very stable product.
These RAD51 paralogs possess a conserved nucleotide triphosphate-binding motif, form a stable heterodimer and bind ssDNA but exhibit weak adenosine triphosphatase activity (27, 32, 39).
Write better and faster with AI suggestions while staying true to your unique style.
Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.
Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com