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The catalytic nucleophile Cys389 lies in a motif different from that in DNA 5-methylcytosine methyltransferases.
This new subclass of lipolytic enzymes possesses a distinct GDSL sequence motif different from the GxSxG motif found in many lipases.
This chromosomal arm contains an origin consensus motif different from other chromosomes and is replicated early during S-phase.
We have identified a novel AR binding motif different from the previously described LXXLL and FXXLF sequences of other coactivators of AR.
Therefore, we can not exclude the possibility that the paralogous copies of S4 in Clostridia are regulated by Zur binding to a motif different from any in our profile.
Equivalent segment of nonhomologous core repeats of the pearl family CvA also exhibits reduced sequence variability, but, instead of hosting a palindrome, it is characterized by a microsatellite-like motif (different from the microsatellite in continuation of core repeats, Gaffney et al. 2003).
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Therefore, it is possible that there are other XlnR-binding functional motifs different from those currently described.
In the prokaryotic world, various heme-containing proteins have motifs different from CXXCH motif, such as the CXXCK motif of NrfA, a bacterial nitrite reductase.
Also, our problem is a de novo or ab initio discovery of local motifs, different from the homology search problem [ 18].
The eukaryotic FMNAT-module is currently classified as a member of the 3'-phosphoadenosine 5'-phosphosulfate (PAPS) reductase-like family belonging to the "adenosine nucleotide α-hydrolase-like" superfamily, which has motifs different from those of NTs.
To uncover over-represented motifs different from the known core elements we examined 857 (25.3% of the total number) promoter sequences with no one of four known core elements by the program MEME at positions from -35 to +35 bp from TSS. Analysis revealed four statistically significant motifs.
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