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Exact(8)
A cross-species comparison of the IAB7b enhancer reveals an evolutionarily conserved signature motif containing two FUSHI-TARAZU activator transcription factor binding sites.
In this context, we report on the direct conjugation of the protein A mimicking peptide Z33, a motif containing two α-helices, to linear hydrocarbons to create self-assembling immuno-amphiphiles (IAs).
At the C-termini they end with a characteristic motif containing two consecutive tryptophans (Additional file 7).
The highest affinity was found for an artificial motif containing two perfect 8-bp tandem repeats: CCTGTGAAaatCCTGTGAA (Schaaf and Bott 2007).
Then a motif containing two 8 bp tandem repeats with a linker of 3 bp were searched in these sequences using the CUBIC program [ 15].
In silico analysis of the L1 integration site indicated that it bisected a palindromic motif containing two 8 bp units differing by one nucleotide and separated by 3 bp.
Similar(52)
For all the 217 query proteins, WildSpan successfully found at least one motif containing five blocks.
TNF receptor 1 (TNFR1) is a member of the death domain superfamily and comprises an extracellular motif containing four cysteine-rich domains, a transmembrane domain, and an intracellular death domain.
This sequence variation in the NLS had been described to affect the binding of importin α/β and subsequently affect the nuclear translocation kinetics since the AK RNF RR motif containing three arginine's (as found in PKCι) enables a direct binding of importin β instead of a sequential binding of importin α followed by importin β (Palmeri and Malim, 1999).
In the case of GDH4 from Chlorella sorokiniana (Fig. 1), the nicotinamide ring is probably adjacent to a very well conserved motif containing three lysine residues: K-G-G-x-R-x(12,23 -L-x 6)- K-x(4,6)-P-x-G-G-x- K202 (according to amino acids position of Ref).
This motif contains two phosphotyrosine residues separated by one residue (sequence pYIpYV where pY indicates a phosphotyrosine).
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