Sentence examples for motif and context from inspiring English sources

Yet the level of conservation of motif and context binding topologies varied considerably among families.

More specifically, our study has quantified the energetic contribution of the interaction consensus motif and context residues, respectively, to binding.

To quantify the contribution of motif and context to the interaction, we used the FoldX package [37], [38] to conduct in silico alanine scanning experiments.

Since motif and context RMSD distributions did not show a normal Gaussian behaviour, standard deviations could not be used to compare them properly.

We also used these transformations to calculate the Cα RMSD between the motif and context residues of the native and chimera protein pairs.

Here we systematically identify all instances of peptide-mediated protein interactions of known 3D structure, based on the motif patterns collected in ELM, and use them to explore the individual contribution of motif and context to the global binding energy.

To further test this hypothesis, we studied the topological and energetic compatibility of linear motifs and context residues in the peptide-mediated protein interaction pairs identified here.

Moreover, we found that both the CpG motifs and the context of the sequence surrounding the CpG motif are important for the immunostimulatory activities.

This is particularly difficult for some histone modifications such as methylation or acetylation of H3K9 and H3K27 which occur within an identical amino acid context (ARKS motif) and make the readout of the target peptide sequence outside of this central motif vital as well.

To conceptualize information on kinase structural motifs and to provide context for cancer variants, we modified the ProKinO schema to add new properties to two classes, namely the Mutation class and Motif class.

PU values are known to be strongly associate with GC content of the motifs and the surrounding context [ 2], therefore it would be most informative to evaluate the difference in the distribution of PU values for the same group of elements surrounded by wild type and dinucleotide reshuffled contexts.