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Standardized residuals were extracted from the chi-square test and used to determine enrichment of certain categories [ 37], followed by a chi-square test comparing the enrichment of variable, mostly variable and discordant genes in boundaries, individually against genes with no call.
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Fully variable escape genes were not enriched in boundaries (p value >0.95) whereas mostly variable escape and discordant genes each had an approximately threefold enrichment (from 2 to 6%% of genes for mostly variable escape (p value <5*10−4) and from 7 to 20 % for discordant genes (p value < 4*10−7)) (Fig. 4c).
This in general could not be confirmed in the protocols using diclazuril, which showed a much lower and mostly variable efficacy pattern.
The variable escape and mostly variable escape categories (8 %) agreed with the Carrel studies; however, the Cotton studies have large differences in the amount of genes they call variable escape.
There is an enrichment of discordancies and calls of mostly variable escape from XCI at putative XCI boundaries.
Genes called escape by mCH were enriched for the mostly variable escape category while being strongly enriched for the escape and mostly escape categories and depleted for the subject category.
Genes which mostly variable escape were most often in escape domains and boundary regions suggesting variation in escape genes.
These discordant and variable genes are spread throughout the different boundaries; 42 % of boundaries have discordant or variable genes in them and 45%% of all the discordant genes and 60%% of all the mostly variable escape genes are in boundaries.
If your costs are mostly variable (ie can be lowered quickly) then you can assume more risks.
Online is also a very profitable model because costs are mostly variable.
These are mostly variable speed drives (VSDs) for the many motor loads found aboard ships.
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