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Second, the protein families represented in today's sequence databases are often more complex, with multidomain architectures, large unstructured (natively disordered) regions, numerous splicing variants, etc. Third, the new sequences are mostly predicted by automatic methods and thus, contain a significant number of sequence errors [33], [34].
In the human lineage, W→S substitution rates are mostly predicted by meiotic recombination, whereas in the mouse lineage, they are mostly predicted by CpG odds ratio.
Changes in thyroid hormone concentrations were mostly predicted by baseline hormone concentrations.
Coding regions are mostly predicted by automatic methods, but the relationship between genes, transcripts and proteins is complex and automated genome annotation is not completely accurate.
Regarding all three thyroid axis hormones that we measured, changes in their concentrations after treatment were mostly predicted by concentrations at baseline.
Firstly, for each identified differentially expressed miRNA, we got its target genes from MicroCosm Targets database (http://www.ebi.ac.uk/enright-srv/microcosm/htdocs/targets/v5/), in which the candidate miRNA-target relationships were mostly predicted by miRanda algorithm [ 22].
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The multiple regression analysis showed that e-learners satisfaction can mostly be predicted by learner interaction with others.
Protein-coding genes in the transcriptome have mostly been predicted by classical methods such as six-frame translation of transcripts.
In 1992, Conservative leader John Major over-performed pre-election polling that mostly predicted a Labour victory.
Climate models mostly predict an increase in annual maximum temperatures in the region of 1 to 2C by 2050.
Systematic differences in microblogging behaviors were found mostly in the direction predicted by the findings of previous studies on differences in national culture; however, we also report new and interesting findings that contribute to the knowledge base.
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