Your English writing platform
Discover LudwigSuggestions(5)
Exact(4)
Their up-regulation targets mostly cell cycle regulatory genes [15], [16].
The overlapped genes are also mostly cell cycle related, including BUB1, CDC20, CCNB1, etc.
The proteins being made during oocyte maturation are mostly cell cycle regulators needed to advance the oocyte through meiosis.
In our study, one of the points of interest was that as time progressed and even though the biological processes were very different across doses at 3 h, the response - by the set of common DE genes- to both 10 cGy (low) and 100 cGy (high) doses of X-ray radiation was similar in terms of the biological pathways (mostly cell cycle processes) affected at 24 h.
Similar(56)
In a recent study, Dai and coworkers [ 58] showed that within a group of patients with high estrogen receptor there is a group of 50 mostly cell-cycle genes that are able to predict the occurrence of metastases.
Genuine cancer cure requires elimination of cancer stem cells which have a mostly quiescent cell cycle profile and are capable of self-renewal.
Taken all together, these findings imply that TLR-1/2 triggering could amplify the Velcade-induced expression of genes, which mostly inhibit cell cycle (cell proliferation) or control apoptosis, in part through the p53 signaling pathway.
Of these, GO terms in LS were mostly related to cell cycle and cell junction, whereas intriguingly in SG, they were mostly related to cell cell signaling and synapse function (Fig 3I).
The most represented BP classes were: (i) metabolism (52.9% and 55.9% in VSa13 and VSa16 cells, respectively), (ii) establishment of localization (16% and 16.1%; mostly related to transport), (iii) cellular processes (14.4% and 12.4%, mostly related to signaling) and (iv) regulation (7.8% and 6.9%, mostly associated to cell cycle).
Here, we studied protein expression profile changes using Panorama antibody microarray chips that contain antibodies to 224 proteins (or their phosphorylated forms) involved in cell signaling that included mostly apoptosis, cytoskeleton, cell cycle and signal transduction.
Our results indicate that at low dose the cells are involved in adaptive responses while at the high dose, they are mostly involved in cell cycle processes.
More suggestions(4)
Write better and faster with AI suggestions while staying true to your unique style.
Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com