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An influential Internet-based educational program paid for by the company focused on specific studies that highlighted Avandia's advantages without discussing one of the drug's most worrisome side effects, increased levels of the lipids implicated in heart disease.
Jamaison Schuler, a spokesman for Eli Lilly, pointed out that the new study, at eight weeks in length, had not lasted long enough to pick up the most worrisome side effect associated with the older drugs: Parkinson's-like movement problems, which are often irreversible.
Roche is developing a torcetrapib-like drug that does not raise blood pressure, thought to be the Pfizer pill's most worrisome side effect.
In fact patients who have received ECT report memory impairment to be the most worrisome side effect [ 11, 12].
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The drawback is that loosening the restraints on the immune system can lead to dangerous side effects, the most worrisome being colitis and diarrhea, but also hepatitis, endocrine dysfunction and skin problems.
Xtandi has its own side effects, however, the most worrisome being seizures, which were suffered by about 1 percent of men taking it in the clinical trial.
Intravenous colchicine has fewer gastrointestinal side effects than oral colchicine, although its primary and most worrisome complication is bone marrow suppression, which can be lethal.
The Canadian novelist Margaret Atwood defines the subject of her book "Payback: Debt and the Shadow Side of Wealth" — which originated as the 2008 Massey Lectures in Toronto — as "one of the most worrisome and puzzling things I know: that peculiar nexus where money, narrative or story, and religious belief intersect, often with explosive force".
The most worrisome involved Johnson.
The third was the most worrisome.
It is also the most worrisome.
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CEO of Professional Science Editing for Scientists @ prosciediting.com