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But the number of patients with the potentially faulty leads has made this the most widespread problem yet involving a heart device.
"The unethical use of placebo controls in clinical trials is the most widespread problem in medical research today," Dr. Weijer said in a telephone interview.
The most widespread problem to result from the new laws, advocates for the poor say, is mistakes in the amount of food stamps allotted to immigrant families.
But in places like this small, dusty town, located high on the Tibetan plateau in the western Chinese province of Qinghai, the most widespread problem is the dislocation of nomadic communities that comes with rapidly enforced top-down development.
The most widespread problem seen on BlackBerrys — and on other platforms — are commercial spyware programs like FlexiSPY, which are secretly installed by someone — usually a jealous spouse — who wants to track a phone owner's location, listen to the calls and read text messages and e-mails.
"The problem of Islamist extremism and charities... is not the most widespread problem we face in terms of abuse of charities, but is potentially the most deadly.
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One of the most widespread problems among Muslims is the feeling that modernity has left them behind.
The mountain lion, a fast predator with paws the size of a catcher's mitt, poses the most widespread problems throughout the West.
The fuel shortage has emerged as one of the most widespread problems after the storm, worsening the suffering in the region.
But the investigation didn't find the pathogens traditionally associate with pork -- trichinosis and salmonella -- to be the most widespread problems.
Tooth decay is one of the most widespread health problems and it is thought around a third of UK children aged 12 have visible tooth decay.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com