Although the gene encoding apolipoprotein E is most well established as influencing risk of late onset AD, several other gene polymorphisms have also emerged from recent studies as having a modest effect on AD risk (Table 1).
At the moment, the application of detection and genotyping of human papillomavirus in management of cervical cancer is one of the most well established appliances of molecular targets in gynaecological cancers.
MPTP treatment of the crab-eating macaque is one of the most well established models of Parkinson's disease [ 39].
One of the most well established trends of predominantly self-fertilizing species is their reduced flower sizes compared with outcrossing species [ 1, 17].
The most well established functions of the small intestine are the digestion of food and absorption of nutrients.
The DIS is one of the oldest and most well established measures of DSM-IV substance use disorders, but caution is urged in the interpretation of these findings until additional reliability studies of DIS-assessed DSM-IV IUDs are performed.
23 27 Increased age is among the most well established predictors of C. difficile risk, and could relate to increased frailty, immune senescence and high rates of hospital contact and antibiotic exposure, but may also be driven by an age-related reduction in the protective diversity of the gut microbiome.
One of the most well established links between a pattern of mutation and environmental exposure is ultraviolet light induced mutation in the p53 gene.
The most well established tactic for the analysis of monosaccharaides, such as glucose, relies on derivatization procedures, using reagents as 2,4-dinitrophenylhydrazine (DNPH).
Cognitive behavioral therapy (CBT) and interpersonal therapy (IPT) are among the most well established therapies for the treatment of depression.
Family history of breast cancer is one of the most well established, widely accepted risk factors for this disease.
