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While there was a large range in virulence with AMC24 being the most virulent strain, with a mean LD50 of 18 CFU and LMG140549T being the least virulent with an LD50 of >10,000 CFU, all but LMG140549T were statistically indistinguishable from each other (Figure 2).
However other studies have found mixed infections to produce transmission stages from more than one strain of parasite in spite of the overall virulence matching that of the most virulent strain [ 29, 31].
Most studies have found either that mixed infections are more virulent than single infections [ 25- 29], or that virulence equalled that of the most virulent strain [ 23, 25, 30- 32].
Although the finding that virulence matched that of the most virulent strain might suggest that that strain has outcompeted the less virulent strain, in some studies the transmission stages produced were from the both strains [ 29, 31, 33], or even entirely from the less virulent strain [ 23].
Parasite heterogeneity may not have effected virulence or the infection dynamics either because the most virulent strain outcompeted the others, or because the interaction involved scramble competition that was impervious to parasite heterogeneity.
This was also the case in the current study, in which the virulence of the mixed infection was the same as that of the most virulent strain in the infection.
Similar(32)
Based on clustering analysis, dominance of the most virulent strains assigned to the cluster with seven virulence factors encoded by the following genes, papC, sfaD/ E, cnf1, usp, agn43, hlyA and iutA, was found.
Based on clustering analysis within the specified group, dominance of the most virulent strains assigned to the cluster with seven virulence factors encoded by the following genes, papC, sfaD/ E, cnf1, usp, agn43, hlyA and iutA, was found (cluster 2 in Table 4).
The multidimensional clustering analysis confirmed the dominance of the most virulent strains assigned to the cluster 2, with seven virulence factors encoded by the following genes, papC, sfaD/ E, cnf1, usp, agn43, hlyA, iutA, in bacteraemia.
The most virulent strains killed 95 percent of the herds they attacked.
Research in April revealed that small doses of the drug may block the growth and spread of the most virulent strains of breast cancer.
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