Sentence examples for most variants that from inspiring English sources
For most variants that lack clear evidence as pathogenic variants, it takes only 1 2 min to complete the review process using ClinLabGeneticist.
These high-throughput assays show that most variants that impact transcription induce 1.3- to 2-fold differences in target gene expression [ 73, 74].
Most variants that are included in the genetic profiles shown in Table 2 are derived directly from genome-wide association studies.
These variants tended to account for moderate proportion of gene expression variation is consistent with our expectation that most variants that affect trait variation are either rare or have low-to-moderate effect per allele.
Indeed, a recent genome-wide association study by Soranzo et al. showed that most gene variants that affect A1C levels are likely to do so via erythrocyte biology rather than glycaemic pathways [18].
With an average of >5 amplicons per exon there is enough redundancy for most sequence variants that might alter primer bindings in other amplicons to be detected.
The 1000GP [ 4] is the first project aiming to sequence genomes of a large number of people, to provide a comprehensive resource on human genetic variation and find most genetic variants that have frequencies of at least 1% in the populations studied.
In addition, most of variants that capture the association with obesity from current GWAS are not themselves causative.
Most of the variants that were predicted to be situated around the DNA-binding site and the [4Fe-4S] clustering pocket were found to be functionally defective variants (Fig. 4C).
Since most drug-resistant variants that have been studied are TK deficient and are attenuated both in infectivity and reactivation ability [ 7], we included sampling constraints so that infectivity and reactivation ability were positively correlated.
The UGT1A1 locus has been mapped to chromosome 2q37 [ 17] and one of the most common genetic variants that affects the glucuronidation of bilirubin in Caucasians is a TA duplication polymorphism in the TATA box region of the promoter.
