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The same appears to be the case for the telencephalon, previously found to be the most variable structure among cichlid species from the three African Lakes [32], although that study did not incorporate phylogenetic information.
The olfactory bulbs were previously found to be the most variable structure, in comparison with all the others, with respect to changes in total brain size [23]; and our results suggest that such variability may be the result of adaptation to different ecological niches.
As in mammals the most variable structure in Tanganyikan cichlids was the olfactory bulbs.
Heparan sulphate has the most variable structure, largely because of variations in the sulphation patterns of its chains.
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Tfp have been considered as one of the most variable structures on the bacterial surface due to high frequency gene conversion, resulting in amino acid sequence variation of the major pilin subunit (PilE).
The olfactory bulbs were the most variable brain structure in comparison with all the others, as shown by the fact that this structure showed positive bivariate allometry with all the others and it had the lowest loading on PC1, the size axis, suggesting that its volume is less correlated with whole brain size as compared with other structures.
The next step was to define the most conserved and the most variable secondary structure elements of the cyclin protein molecule.
It is worth highlighting that in mammals the olfactory bulb also appears to be the most variable brain structure and it has even been suggested as an exception to the concerted evolution model [ 13, 14].
In the pea structure, this is the most variable region of the whole structure and, in six out of the eight molecules, sections of it are not resolved at all due to weak electron density.
Analysis of the distribution of the main-chain temperature factor averaged over the total of 12 monomers in the asymmetric units of the Form B crystals also highlights these three loops as the most variable regions in the structure (Fig. 2(B)).
Using a window-size of 5 centered on each residue, we applied Lasso to identify the most variable regions for 1a3s (11 structures; Figure 6A).
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Justyna Jupowicz-Kozak
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