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As judged by sequence analysis, the V01 region, which comprises the homologous region 1 (hr1), is the most variable genomic region among the genotypes present in the Spanish isolates.
Perhaps they are among the most variable genomic regions in these organisms, while mitochondrial DNA and other nuclear sequences are highly conserved [ 10, 11, 14].
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Finally, the viral genetic characterization established that viruses from the case cluster shared a high nucleotide sequence identity in Gn and Gc fragments, the most variable viral genomic regions (6 ).
Borrelia burgdorferi sensu lato (B. burgdorferi s.l)., the group of bacterial species represented by Lyme disease pathogens, has one of the most complex and variable genomic architectures among prokaryotes.
That is, because Domain 1's were found to be the most variable domain, cDNA and genomic sequences coding for Domain 1's were aligned and used to generate a phylogram.
Most evidence for large microbial pan-genomes comes from variable genomic islands.
The remaining 635 HCEs show variable genomic locations from one genome to another.
Twenty-three of the most variable loci among E. coli O157 H7 strains were targeted by the comparative genomic fingerprinting method of Laing et al. [ 13].
S. anginosus was the most variable species sequenced in this study, yielding both the smallest and the largest SAG genomes containing multiple genomic rearrangements, insertions and deletions.
Thus, upregulation of PPARβ/δ appears to occur downstream of individually variable genomic risk, offering a potential target for treatment relevant for most patients.
Since the genomic sequences of host-range phage mutants are almost identical, sequencing PCR amplicons of the most variable regions could distinguish the phages in commercial products from different companies.
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