Suggestions(5)
Exact(6)
The oligomerization domain of rice ALDHs is the most variable domain.
Four of the SNPs (three nonsynonymous and one synonymous) are in the B30.2/SPRY domain, which is the capsid-binding domain and has been described as the most variable domain in other primate TRIM5α sequences [6], [7], [25].
However, these data do confirm findings shown in Table 4 indicating that Domain 1 is the most variable domain.
Conversely, the C-terminal part of N (from aa 384 to aa 532) overlaps antigenic epitopes and is the most variable domain (26 ).
That is, because Domain 1's were found to be the most variable domain, cDNA and genomic sequences coding for Domain 1's were aligned and used to generate a phylogram.
The N-terminal domain of AGOs is the most variable domain, whereas, 'Y-N-K-K'D-E-D-H/DK', 'D-E-D-have have been regarded as the signatures of PAZ, MID and PIWI domains, respectively [ 7].
Similar(53)
In the topology of the ALDH families, the most variable domains (in terms of the electrostatic potential) seem to be the catalytic and cofactor domains.
Evolutionary analysis of plant terpene synthase genes also revealed strong conservation within the C-terminal enzyme catalytic site, with most variable domains observed in the N-terminal part of uncertain functions [ 56].
The complementarity determining regions (CDRs) of an antibody are the most variable segments of the variable domain that are essential for the antibody-antigen binding specificity and affinity [ 14].
To detect a 5-point change on the most variable individual SF-36 domain score (role-physical), with 80% power and 0.05 tolerance of type 1 error, 293 evaluable patients were required, based on a two-sided paired t test, assuming within-subject test-retest correlation of 0.60 and standard deviation (SD) of 34 (data for the US normal subjects).
The most variable of the enzymatic domains between species are the ACP-I domains (95.2% nucleotide identity).
More suggestions(15)
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