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In the Breast Cancer dataset, TSPYL5 was regarded as the most valuable prognostic marker by our methods and by the correlation-based approach used in [ 19].
Systematic review and meta-analytical approaches to identifying the most valuable prognostic markers are needed because (sometimes conflicting) evidence relating to markers is often published across a number of studies.
An evidence-based approach to identifying the most valuable prognostic markers for a given disease is clearly important because it is common for evidence relating to markers to be published across a number of studies, often with conflicting results (Altman, 2001, pp 228 247; Riley et al, 2003a).
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To date, pathologic stage is the most valuable single prognostic attribute in esophageal cancer patients.
In breast cancer to date, the axillary lymph node (ALN) status remains the most valuable individual prognostic factor for disease course and recurrence (McGuire, 1987; Foster, 1996).
The presence or absence of lymph node metastasis is still regarded as the most valuable single prognostic attribute (Goldhirsch et al, 2005).
Taking into account that the presence or absence of lymph node metastases is regarded the most valuable single prognostic factor, these results are interesting.
Of the myriad of cytokines and chemokines that can be measured in the circulation during acute inflammation, IL-6 may be the best studied and most valuable as a prognostic indicator [ 31].
The Robinson [1] classification system is the most valuable in terms of choosing therapy, as well as being of prognostic value for midshaft clavicular fractures.
The Edinburgh classification system is the most valuable in terms of choosing therapy, as well as being of prognostic value for midshaft clavicular fractures.
Genome-scale microarrays (cDNA- or oligonucleotide-based) are most valuable when screening populations of cells for the novel genes reflecting potential diagnostic and prognostic markers or for an identification of novel therapeutic targets.
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