Nature is the most valuable source of therapeutic compounds as enormous chemical diversity is present in millions of species of plants, animals, marine organisms, and microorganisms [ 1].
Hence, the synthesis of berberine chloride was achieved in an overall yield of 68%% from compound 1 (the most valuable starting material) or 50%% from compound 3 (the longest linear sequence).
Sea cucumbers are from those marine organisms that are considered as one of the most valuable sources of structurally diverse bioactive compounds with immense nutraceutical, pharmaceutical, and cosmeceutical potentials [ 6].
Extraction and recovery of valuable compounds are the most common uses for SFE, which operate at low temperatures, in the absence of oxygen, and typically use CO2 as extraction solvent (SC-CO2).
However, the single molecule normalization in combination with the prediction value might be the most valuable representation for the visualization of a compound.
Use of safe plant based compounds is one of the most valuable options to prevent and/or delay the neoplastic inception.
Glandular trichomes (GT) of Artemisia annua produce valuable compounds for pharmaceutical and industrial uses, most notably the anti-malarial artemisinin.
Enantiopure alcohols are one of the most valuable synthons for the production of various biologically active compounds such as pharmaceuticals, agrochemicals, or flavors (Kaluzna et al. 2005; Matsuda et al. 2009; Nakamura et al. 2003; Patel 2008, 2013).
The plant kingdom is an extensive source of valuable compounds with a wide range of applications, most notably, in medicine.
