We reasoned that siRNAs causing significant loss of cell viability (Z≤−3) in all of the cell lines assayed likely represented kinases that are essential for viability in most tumour types or more likely essential for the viability of both normal and tumour cells.
NB7M showed potent activity against most tumour types.
The gold-standard end-point in most tumour types is overall survival (OS).
In a recent study (Went et al, 2004), c-Kit expression was shown to occur infrequently in most tumour types.
Cell cell adhesion has been implicated to be of great importance for the invasive capacity of most tumour types.
We found that the TSGs had the highest mutation frequency in most tumour types and the OCGs second.
Recent data indicate that the sensitivity to detect most tumour types is lower than that of FDG PET.
In summary, these results indicated that TSGs had the highest mutation frequency in most tumour types, and the OCGs were the second.
The pattern for epithelial staining was more complex and revealed more intensive staining in the parenchyma for most tumour types compared with the neoplastic epithelium (Fig. 2).
A core activity is regular MDT meetings (MDMs), held weekly for most tumour types, which brings together all relevant health professionals to discuss and agree patient treatment plans.
