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Third, the duration of most trials has been suggested to be inadequate to show benefits.
16, 18, 20, 21 Fortunately, the most common serious ADE reported in most trials has been infusion site pain, with an incidence of <8%.
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Most trials have resulted in reduced Aedes populations, Oxitec has said.
As a result, most trials have focused on such patients and on younger, healthier subjects than the average patient.
Most trials have focused on the effects of fish oil on people who have had a history of heart trouble.
Most trials have been conducted in single centers.
Importantly, most trials have important methodological flaws and have used inconsistent methods and therapeutic endpoints [29].
Most trials have been conducted to investigate pollution effects and have often focused on calcareous stone [12 14].
Although most trials have used intracoronary delivery, the optimal method is unknown and data suggest that the transendocardial approach may have important advantages.
None the less, DCV have yet to prove an effective cancer treatment modality and most trials have been small and uncontrolled.
The fact that most trials have so far been performed with end-stage cancer patients can largely account for this deficit.
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