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A meta-analysis of OA trials highlights this, with most trials evaluating drug treatments (60%) or surgical procedures (26%) [ 14].
Most trials evaluating renal dysfunction are binary, in that ARF is present or absent; AKI is often not addressed.
The primary analysis of most trials evaluating complex interventions does not differ from that of trials involving single interventions.
Despite their important contribution, most trials evaluating PCT-guided antibiotic therapy present several limitations that preclude their safe extrapolation to the clinical decision-making process [ 3].
The contention is that, given the extensive preliminary work and scientific investment in the development of a new therapy, including preliminary trials to evaluate efficacy, it stands to reason that most trials evaluating such a therapy will be positive.
In addition, the prognostic impact of PCI remains debatable [ 9, 10], and most trials evaluating the potential impact of MTH and emergency PCI on survival have been performed in patients under 75 years of age.
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Most trials evaluated the proportion of patients without MM during the treated PMPs as the primary outcome.
Most trials evaluated surgical interventions, however there were also drug and therapeutic interventions such as the use radiation.
Most randomised trials evaluating antibiotics for COPD were restricted to patients hospitalised for acute exacerbations [ 5].
Most research trials evaluating the efficacy of IBIs were conducted with college students [ 24].
Most clinical trials evaluating the effect of anthelmintic treatment, report the average effect in the study population.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com