Well-known examples are found among plants and their pollinators, and a striking number of the most tightly co-evolved interactions involve moths.
(i.e., those that are the most tightly co-regulated within their module) were selected.
The analysis showed that besides the already known inhibitor of matriptase, HAI-1 encoded by SPINT1, CLDN7, encoding claudin-7, is the gene most tightly co-regulated with the ST14 gene.
In order to compile a shorter list of the most tightly co-regulated genes from each module, the top 10% of genes from each module with highest k.in.in
Much more of the transcriptional variance was explained by seven previously identified axes of variation, each of which was defined as the first PC of ten "blood informative transcripts" [ 24] that were the most tightly co-regulated of hundreds of correlated transcripts.
Thus, within a set of related genes, for example the 282 members of the RRB regulon in S. cerevisiae, the subset of the 44 paired genes are the most tightly co-regulated members of the regulon, even though the gene pairs themselves were scattered across the various chromosomes.
We show that several miRNAs are predicted as statistically significant regulators for various modules of tightly co-expressed genes.
A hub gene, that is a gene which is among the most highly connected within a module, is likely to be tightly involved in the regulatory mechanisms of all those genes with which it is tightly co-expressed.
Mr. Takemura gave the evening's most tightly scripted performance.
Synonyms are "collective, cooperative" and the most tightly connected, "joint".
These were not the most tightly contested affairs.
