Sentence examples for most tightly associated from inspiring English sources

The immunoaffinity purification was carried out in the presence of 1M KCl to remove all but the most tightly associated proteins.

While numerous reports have emphasized that CTL responses targeting Gag are the most tightly associated with the control of HIV replication [2], [10], [11], [12], [13], [14], [15], [16], [17], little is known about the underlying mechanism.

In addition, it may be that the plaque structure would not be maintained if the lipids most tightly associated with the channels were removed.

Moreover, which of these two forms were most tightly associated with chromatin appeared to be dependent on the cell cycle stage.

The present study was undertaken to identify endogenous phospholipids most tightly associated with channels composed of connexin26 (Cx26) or connexin32 (Cx32), with the idea that these are the most likely to have structural and/or functional roles.

Firstly, to identify phospholipids most tightly associated with hemichannels, channels with a cytoplasmic carboxyl terminal epitope tag were purified in a non-ionic detergent that maintains the hexameric form and channel function [ 19, 20].

Instead, our data demonstrate that it is foreign spider diversity that is most tightly negatively associated with colony extinction.

They are not only omnipresent in most genomes, but also tightly associated with various types of genetic variability, from changes in genome size and arrangement to single nucleotide mutations [ 19].

As described above, potentially the most stringent criterion for identifying tightly associated phospholipids is their presence in both hemichannel preparations and isolated plaques.

Given that abnormal TDP-43 function is tightly associated with most ALS cases, the present study provides novel insight into how microglia induce neurotoxicity in ALS, and, more interestingly, suggests celecoxib as a potential therapy for ALS.

The methylation of DNA is considered to be one of the most relevant processes in epigenetics and is tightly associated with cancer.