Furthermore, the βFαG'-loop drifted into cl2 shielding the active site and forming a short α-helix, characteristic for most of the ternary complexes present in the PDB.
We find that most of the ternary complexes formed with RRM, RNA, and LRR domains exhibit positive thermodynamic linkage (cooperativity) that enhances the stability of specific complexes.
This most likely reflects transient ternary complexes that are formed between these proteins and the TCP-1 complex [ 8, 9, 13 15].
It is found that because some of the interaction pairs have overlapping sites, a number of the interactions are mutually exclusive, with the result that ESR1 is at most able to form ternary complexes of the involved proteins.
Most important, such ligands may form ternary complexes with the metal and ascorbic acid (Fridman et al. 1983).
Unlike the hE NADPH complex, most of the chemical shift differences in the hE THF complex relative to the ternary complexes are associated with residues clustered near the vacant cofactor binding site.
Based on these results, we uncover a general principle governing the structure of TF-TF-DNA ternary complexes, namely that the flexibility of the complex is correlated with, and most likely a consequence of, inter-motif spacing.
Functionally, the G1 domain interacts with hyaluronan acid and link protein, forming stable ternary complexes in the extracellular matrix.
Pica, A. et al. Through-bond effects in the ternary complexes of thrombin sandwiched by two DNA aptamers.
Szczepankiewicz, B. G. et al. Synthesis of carba-NAD and the structures of its ternary complexes with SIRT3 and SIRT5.
