Sentence examples for most suitable genes from inspiring English sources

The TAF10 gene was employed as a control housekeeping gene, because TAF10 gene is reported to be among the most suitable genes for use as a reference in qRT-PCR (Teste et al. 2009).

Their expression varied under all variables tested; therefore the ranking of the most suitable genes for the normalization is modified depending on the factors included in the analysis, especially the age of the donor.

In conclusion, we suggest that the use of a selection of the most suitable genes is a valid (and simpler) strategy that produces results equivalent to the use of the entire genome.

Housekeeping genes were selected in a previous study using the RealTime ready Reference Gene Panel (Roche Diagnostics), which contains 19 different reference genes to facilitate the identification of the most suitable genes from 8 different carcinoma samples.

Actin B (ACTB) expression was found to be almost identical in untreated and IFN-treated PBL and also in untreated, IFN- or IC-treated MDM and was thus selected as the most suitable gene to normalize our results in both cell types.

Treatment of the patient with the most suitable gene therapy or immunological or pharmaceutical intervention in order to eliminate cancer cells or to slow or stop cancer progression during somatic cancer evolution.

The GAL network is arguably the most suitable gene network to test our model due to the network's well-characterized [ 14– 18] nature in terms of its components and their interaction topology.

For relative quantification of FABP mRNA expression, we also determined the two genes TATA box-binding protein (TBP) and peptidylproline isomerase A (PPIA) verified in a previous study as most suitable reference genes for gene profiling studies in renal cell carcinoma tissue [ 7].

For relative quantification of B-FABP mRNA expression, we also determined the two genes TATA box-binding protein (TBP) and peptidylproline isomerase A (PPIA) verified in a previous study as most suitable reference genes for gene profiling studies in renal cell carcinoma [ 17].

As numerous studies reported that commonly used reference genes are not constantly expressed under different experimental conditions, we selected the 20 most suitable reference genes among 62 candidate genes previously reported as 'housekeeping' genes, based on their expression stability and correlation.

Our findings strongly confirm that RPLP0 and TFRC are the most suitable reference genes for HUVEC gene expression experiments subjected to hypoxia and/or hyperglycemia for the given experimental conditions.