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Therefore, preclinical evaluation of Bortezomib-based combinations in a given tumor type as well as studies of the underlying mechanisms of drug interaction and of the most suitable administration schedule are critical for the rational design of synergistic combination therapies with Bortezomib for clinical translation.
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Oral cavity mucosa is one of the most suitable drug administration routes.
The parallel application of instruments in the two cohorts and modes of administration (CAPI and CATI) will on the one hand allow us to identify those tools that are most suitable for telephone administration.
The aerodynamic performance showed that the milling time of 30 min was most suitable for inhalable administration.
In addition, the most suitable route of fluid administration and the type of fluid was doubtful.
Therefore, if using atipamezole for reversal of KX anaesthesia in rats, it has to be considered which is the most suitable moment for the administration in this species.
It is likely that this is one of the most suitable cancers for oral administration of curcumin, because of low bioavailability for other non-gastrointestinal cancers, and the increasing diagnosis worldwide of pre-malignant conditions such as Barrett's oesophagus.
Based on the above studies, it was noted that intermittent irradiation by 4.3 4.5 mW/cm LED combined with intravenous administration of 60 mg/kg of rose bengal was the most suitable condition for the establishment of progressive thrombosis model.
The first or second set of subtracted images after contrast administration is generally the most suitable for evaluation of breast vascularity.
We recommend that studies need to be performed to determine the most suitable and clinically more useful method of administration of fish oil by comparing intravenous versus enteral feeding of fish oil and/or GLA-EPA/DHA supplementation.
Considering the impressive efficacy of the protracted treatment schedules with IDN 5390 s.c., the oral route of administration was investigated, as the most suitable for daily treatment.
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