Sentence examples for most substantial role from inspiring English sources

Irina Palm, however, is unquestionably her most substantial role to date.

This is what lured the 63-year-old Gere back to play his most substantial role in years.

His most substantial role was Lord Raglan in Tony Richardson's The Charge of the Light Brigade.

In Gielgud's ten other films from this period, his most substantial role was Clive Langham in Alain Resnais' Providence (1977).

Second, astrocytes play the most substantial role in maintaining an intact blood-brain barrier (BBB) [ 54].

Data suggest that smoking has immunosuppressive effects through the various substances contained in cigarette smoke, among which nicotine has the most substantial role.

Wardrobe discomfort notwithstanding, however, period dramas often seem to provide the most substantial roles for older actresses, raising the disquieting thought that perhaps older women were accorded greater status in Victorian times than they are today.

Emmanuelle Chriqui aces one of the most substantial roles of her long career, playing Donna, a small-town ex-prostitute who lives with her brain-damaged teenage son at the bed-and-breakfast she runs.

Hall, in her most substantial screen role for years, reminds us just how the movies have largely wasted her alert and deeply sympathetic presence, while Edgerton picks out a serious callous streak in Bateman that is new, fascinating and – given the reviews for Horrible Bosses 2 –potentially career-saving.

Relishable performances include Karina Fernandez's priceless cameo as a flamenco teacher; Kate O'Flynn and Caroline Martin as Poppy's contrasting sisters; and, sustaining a beautifully developed thread of level-headedness, Alexis Zegerman as Poppy's flatmate Zoe, surely the most substantial best-buddy role ever seen in cinema.

Perhaps the two most substantial are the role of Dpp in promoting Sog cleavage, and the explanation of some of the classical mutants.