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Establishing closer links on this level might have the most substantial effect in the long run.
The most substantial effect of such measures may be to convince kids that their adult authority figures are hypocritical bullies.
From the American perspective, the most substantial effect of the British elections is likely to be on the so-called special relationship.
The most substantial effect was seen with 0.125 mg/kg of mecamylamine, which caused a significant (p < .05) improvement relative to the saline control condition.
From the U.S. perspective, the election's most substantial effect is likely to be on the so-called special relationship between Britain and America, which for the past few years has hung in an uncertain limbo.
The most substantial effect of the new guidelines — which the agency will promulgate to regional offices that issue permits — will be to benchmark the permissible levels of mining runoff likely to be introduced into the waterways surrounding a proposed project.
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One of the most substantial effects arises from a change of target species.
Results to date show that the program's most substantial effects were to reduce poverty and material hardship during the 3 years in which the rewards were offered.
Consequently, eCall (equipped with accurate location information such as Global Positioning System, GPS) is expected to have the most substantial effects on minor rural roads, at night-time, and in off-peak traffic.
"The most substantial effects will be experienced by harmful and hazardous drinkers, who are more likely to consume cheaper and higher-strength alcohol products". But Alex Loveland, a recovering alcoholic who supports people with dependency, is worried that it will not help them.
The inhibition by ruthenium red of Ni2+-evoked Ca2+ signals need not reflect an action at PM RyR, because ruthenium red is membrane-impermeant and its most substantial effects on RyR appear to be mediated by binding to its cytosolic surface (177).
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com