Sentence examples for most substantial causes from inspiring English sources

Nicky Morgan, the education secretary and equalities minister, spoke earlier this month about one of the most substantial causes behind the pay gap being the fact that women are still far less likely to work in higher paid industries.

The most substantial changes were caused by the D734R mutation, which elevated EC50 to such a great extent that 10 mM intracellular calcium, the highest concentration of calcium used in this study, was unable to activate the mutant channel.

Individual resistance vessels were therefore pre-constricted with whichever agent was found to cause the most substantial and sustained constriction.

In the × dimension (phosphoproteins), the data indicated that the change by time point tended to cause the most substantial response in phosphoprotein levels.

Combining the two sets of mutations, however, appeared to cause the most substantial loss of Vpu function, suggesting a potentially parallel nature for these pathways.

The most substantial changes in cosmic ray parameter are caused by emissions of the corona substance and subsequent changes in parameters of the interplanetary field and solar wind (Vecchio et al. [2012]).

The most substantial effect was seen with 0.125 mg/kg of mecamylamine, which caused a significant (p < .05) improvement relative to the saline control condition.

China's increase has been the most substantial.

Portraiture accounts for the most substantial works here.

This will be the most substantial change since the 1940s".

The most substantial additions unveiled yesterday are underground.