Sentence examples for most substantial alteration from inspiring English sources

The changes, which are shaping up to be the most substantial alteration ever to a campaign calendar in a single election cycle, have heightened the volatility of the most wide-open presidential race in 50 years, one with large and well-financed fields of contenders.

The most substantial alteration takes place in the estimated effect of white cheese, where the measurement error corrected analysis shows a non-significant protective effect.

Numerically, the most substantial alterations were the change in the genus Bifidobacterium (e.g. Bifidobacterium adolescentis), which increased approximately 10 fold (from 2 3% to 18 30%) in three subjects through RS4.

At 12 weeks of age, the most substantial alterations to metal concentrations were observed in the spinal cord.

This will be the most substantial change since the 1940s".

The dual front-facing camera is the most substantial change.

Marius the Epicurean (1885) is his most substantial work.

Irina Palm, however, is unquestionably her most substantial role to date.

It is certainly the most substantial game for the Wii.

China's increase has been the most substantial.

Portraiture accounts for the most substantial works here.