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Most studies were cross-sectional in design.
Most studies were small and may have been underpowered.
Most studies were quantitative (89%) and used inferential statistics (63%).
Most studies were descriptive cross sectional in design (n = 39).
Most studies were microbiology cultures (68%%), laboratory studies (16 %), or microbiology serologies (10%%).
However, most studies were underpowered and limited by their case-control design.
Most studies were performed on mice using an injection route of exposure.
Thus far, most studies were performed in aquatic ecosystems; only few studies focused on soil ecosystems.
Most studies were short-term, and only a handful compared treatment options in different therapeutic classes.
Most studies were descriptive and suggested that relationship-oriented management practices will promote better outcomes.
Most studies were performed with a voluntary running paradigm (e.g. running wheel) in mice.
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