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Most studies utilizing SEM use samples that range in size from 3 5 mm (Eveling and McCall, 1983; Sargent, 1983; Eveling, 1984).
Stable isotope labelling or SIL (mainly with C and N) is an essential component of most studies utilizing discovery metabolomic techniques.
Although most studies utilizing NGS data to date have focused on 'quads' or 'trios' [ 47- 51], studying large and/or consanguineous families can maximize the utility of filtering strategies and statistical approaches for identifying disease-contributory variants in genetic disease [ 52].
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Most studies utilized self-report measures of child feeding practices that have not been validated specifically for use with fathers.
And, most studies utilize wood and municipal waste feedstocks rather than crop residues though the later are often available in agriculture.
Most studies utilize either aerobic or anaerobic microbial consortia separately, however the existence of mixed microbiota in oil reservoirs with both aerobic and anaerobic consortia actively participating of the biodegradation process should be considered.
Regarding sample size in step 3 and number of items, a particularly noteworthy finding was that most studies utilized sample sizes smaller than the rule of thumb that the minimum required ratio should be 10 1 (e.g., Turker 2009; Zheng et al. 2010).
Most studies utilize the overall in-hospital mortality or 28-day in-hospital mortality as endpoints.
Most studies utilized excisional biopsies, which provide optimal quantity of tissue and allow its morphological assessment.
This is important, as most studies utilized a reactive approach to recruitment, and the study samples recruited through this approach might differ from proactively recruited samples.
At the expression level, most studies utilized immunohistochemistry to measure SDHA and SDHB protein, and showed loss of SDHB in pheochromocytoma paraganglioma tumors (van Nederveen et al. 2009).
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