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On the contrary, the expression of most studied targets became up-regulated in DA rats and increased over time in all the studied compartments.
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Its most studied target is S6 kinase, which phosphorylates S6 and rapamycin prevents this phosphorylation.
HER2 is one of the most extensively studied targets for cancer therapy.
One of the most extensively studied targets is the interleukin-13 receptor alpha 2 (IL13R α2) [ 11].
One of the most extensively studied targets is the interleukin-13 receptor alpha chain variant 2 (IL13R α2).
The PTEN gene and the AKT/PI3K pathway are among the most intensively studied targets in cancer research.
One of the most extensively studied targets of PDK-1 was AKT, which can be activated by phosphorylation on two residues (T308 and S473) for full oncogenic activity (Bellacosa et al, 1998).
Unfortunately, most studies target a 478 bp fragment of the cytochrome b (cytb) gene, which often cannot be used to separate lineages from different genera found in mixed infections that are common in wildlife.
While most studies targeted women in the community, none of them targeted those with sedentary occupations.
In most studies, target heart rates for scanning were below 60 65 beats per minute (bpm).
However, empirical studies testing the hypothesis that body size underlies species-specific responses to fragmentation remain scant because most studies target single species (but see Davies et al. 2000).
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