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The TGF-β pathway is one of the most studied pathways [ 6- 10].
Mitochondrial dysfunction, one of the most studied pathways, can result in oxidative stress and energy supply abnormality for neuronal cells [ 8].
In this respect, the most studied pathways are the WNT (Wingless-type), SHH (sonic hedgehog), NOTCH and PTEN (phosphatase and tensin homolog deleted on chromosome ten) pathways.
The Nrf2-dependent antioxidant response, the heat shock response, the NF- κB inflammatory pathway, and the PPAR γ are among the most studied pathways regulated by electrophiles and participate in transducing the beneficial actions of electrophilic omega-3 PUFAs.
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The mammalian target of rapamycin (mTOR) pathway is the most studied pathway regulating autophagy.
In fact, the most studied pathway controlling the consolidation of neurites involves signaling through neurotrophin receptors to a Ras-dependent, mitogen-activated protein kinase (MAPK) cascade [ 33].
The PHO regulatory system is one of the most well studied pathways in Saccharomyces cerevisiae.
In this work, we analyzed the phenotype capacities emerged from a constructed metabolic network conformed by the most experimentally studied pathways sustaining cancer cell growth.
The flavonoid biosynthetic pathway is one of the most extensively studied pathways in plant specialized metabolism [ 1].
DAF-2 insulin/IGF-1 signalling is one of the most extensively studied pathways regulating host infection outcomes in C. elegans.
MAPK pathway is one of the most extensively studied pathways involved in tumorgenesis [ 48] and has proven to be a major target of Meq during tumor formation by chromatin immunoprecipitation sequencing [ 49] and RNA sequencing [ 50].
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