Although the CYP4A12 is most studied source of 20-HETE, whether other CYPs contribute is unknown.
The final model allows the possibility of a comprehensive set of predictors (more than most studies) to contribute to explaining quality of life, enabling each predictor to have a net contribution (Fritzell & Lundberg 2007; Steptoe, Demakakos, & de Oliveira, 2012).
The study contributing most samples and data was a multi-country prospective observational cohort study aimed at characterizing novel safety biomarkers for vaginal HIV microbicide development in East and South Africa (referred to as the Vaginal Biomarkers Study).
For the main meta-analysis of ex smoking, the studies contributing most to the total weight for all lung cancer were STOCKW/sexes combined (22.4% of the total of 4,739), followed by BROWNS/males (8.5%) and BROWNS/females (6.5%).
For the main meta-analysis, the studies contributing most to the total weight for current smoking for all lung cancer were STOCKW/sexes combined (17.8% of the total of 6,750) followed by BROWNS/males (6.0%) and BROWNS/females (5.4%).
This population-based survey from Lithuania, however, was by far the most methodologically sound of the studies contributing to it.
Sensitivity analyses indicated that the independent study contributing the most to heterogeneity was conducted by Kohno et al. [ 23].
As a sensitivity analysis, we re-ran the fixed effect meta-analysis after excluding the study contributing the most to the heterogeneity.
Meanwhile, we identified two studies contributing the most to the heterogeneity in the sensitivity analysis, both of which measured MACC1 expression via IHC [ 17, 22].
For the main meta-analysis, the studies contributing the most to the total weight are the same as for the corresponding meta-analysis for ever smoking: ZIELI2/females for COPD (11.7% of the total of 4,226), and LAVECC/sexes combined for CB (11.4% of 4,326) and emphysema (61.9% of 287).
